*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NL3663500
CHEMICAL NAME           : 1H-Indole-3-acetic acid, 2-methyl-,
                          2-(((2-methoxyphenyl)amino)thioxomethyl)hydrazide
CAS REGISTRY NUMBER     : 54648-86-1
LAST UPDATED            : 198512
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H20-N4-O2-S
MOLECULAR WEIGHT        : 368.49
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Methyl-3-(1-(4-o-anisylthiocarbazido))acetylindole
   * 2-Methyl-1H-indole-3-acetic acid  
   2-(((2-methoxyphenyl)amino)thioxomethyl)hydrazide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   CNJPAZ Canadian Journal of Pharmaceutical Sciences.  (Toronto, Ont., Canada)
    V.1-16, 1966-81. Discontinued.  Volume(issue)/page/year: 9,108,1974
 
                            *** END OF RECORD ***