*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NK7925000
CHEMICAL NAME           : 1H-Indazole,
                          3-(N,N-dimethylpropoxy)-1-(alpha,alpha,alpha-trifluor
                          o-m-tolyl)-
CAS REGISTRY NUMBER     : 21487-14-9
BEILSTEIN REFERENCE NO. : 0845272
REFERENCE               : 5-23-11-00245 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H20-F3-N3-O
MOLECULAR WEIGHT        : 363.42
WISWESSER LINE NOTATION : T56 BNNJ BR CXFFF& DO3N1&1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   3-(N,N-Dimethylpropoxy)-1-(alpha,alpha,alpha-trifluoro-m-tolyl)-1H-indaz
     ole
   * ITF 621
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 25,386,1970
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 670 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 25,386,1970
 
                            *** END OF RECORD ***