*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NK5135000
CHEMICAL NAME           : 1,3-Indandione, 2-benzyl-2-(4-piperidino-2-butynyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 22019-28-9
LAST UPDATED            : 198401
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C25-H25-N-O2.Cl-H
MOLECULAR WEIGHT        : 407.97
WISWESSER LINE NOTATION : L56 BV DV CHJ C1R& C2UU2- AT6NTJ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Benzyl-2-(delta-piperidinobutynyl)indan-1,3-dione hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 118 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - muscle contraction or spasticity
   Behavioral - antipsychotic
REFERENCE :
   PCJOAU Pharmaceutical Chemistry Journal (English Translation).  Translation
   of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013)  No.1-
   1967-  Volume(issue)/page/year: 2,428,1968
 
                            *** END OF RECORD ***