*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : NJ8620830
CHEMICAL NAME : 3,6-Imino-1H-2-oxa-11c-azanaphth(1,2,3-cd)-azulene-5-
carboxylic acid, 2a,3,4,5,6,6a,7,11b-
octahydro-11-methoxy-12-methyl-, monocitrate
CAS REGISTRY NUMBER : 101311-75-5
LAST UPDATED : 198909
DATA ITEMS CITED : 4
MOLECULAR FORMULA : C18-H22-N2-O4.C6-H8-O7
MOLECULAR WEIGHT : 522.56
COMPOUND DESCRIPTOR : Drug
Mutagen
SYNONYMS/TRADE NAMES :
* KW2152
* Quinocarmycin citrate
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 13900 ug/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
Endocrine - other changes
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
47,1516,1987
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 22 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540,
08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year:
12,556,1987
** MUTATION DATA **
TYPE OF TEST : DNA inhibition
TEST SYSTEM : Rodent - mouse Leukocyte
DOSE/DURATION : 340 umol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
47,1516,1987
TYPE OF TEST : Mutation test systems - not otherwise specified
TEST SYSTEM : Rodent - mouse Leukocyte
DOSE/DURATION : 12 umol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
47,1516,1987
*** END OF RECORD ***