*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NJ5843300
CHEMICAL NAME           : Imidazo(1,2-a)pyrimidine-6-carboxylic acid,
                          1,2,3,5-tetrahydro-1-methyl-5-oxo-2-phenyl-
CAS REGISTRY NUMBER     : 141234-27-7
LAST UPDATED            : 199406
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H13-N3-O3
MOLECULAR WEIGHT        : 271.30
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   1-Methyl-2-phenyl-5(1H)-oxo-2,3-dihydroimidazo(1,2-a)pyrimidine-6-carbox
     ylic acid
   *   1,2,3,5-Tetrahydro-1-methyl-5-oxo-2-phenylimidazo(1,2-a)pyrimidine-6-car
     boxylic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 460 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year: 44,67,1992
 
                            *** END OF RECORD ***