*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NJ0570000
CHEMICAL NAME           : 2-Imidazolidinone
CAS REGISTRY NUMBER     : 120-93-4
LAST UPDATED            : 199710
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C3-H6-N2-O
MOLECULAR WEIGHT        : 86.11
WISWESSER LINE NOTATION : T5MVMTJ
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Tumorigen
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Ethylene urea
   * 2-Imidazolidone
   * Urea, 1,3-ethylene-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 17,235,1982
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1000 mg/kg
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Blood - tumors
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB223-159
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 15 mg/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - male fertility index (e.g. # males impregnating
   females per # males exposed to fertile nonpregnant females)
REFERENCE :
   85GUAJ "Antifertility Compounds in the Male and Female," Jackson, H.,
   Springfield, IL, Charles C. Thomas, 1966  Volume(issue)/page/year: -,37,1966

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 83666
       No. of Facilities: 159 (estimated)
       No. of Industries: 3
       No. of Occupations: 11
       No. of Employees: 4032 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 83666
       No. of Facilities: 76 (estimated)
       No. of Industries: 3
       No. of Occupations: 4
       No. of Employees: 6452 (estimated)
       No. of Female Employees: 347 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***