*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NI7670000
CHEMICAL NAME           : 1H-Imidazole, 1-methyl-2-nitro-5-vinyl-
CAS REGISTRY NUMBER     : 39070-08-1
BEILSTEIN REFERENCE NO. : 0957472
REFERENCE               : 5-23-05-00391 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C6-H7-N3-O2
MOLECULAR WEIGHT        : 153.16
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * L 8580
   * 1-Methyl-2-nitro-5-vinyl-1H-imidazole
   * MEV
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 480 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 20,656,1977
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 800 umol/L
REFERENCE :
   JGMIAN Journal of General Microbiology.  (Soc. for General Microbiology,
   Journal Sales, 62 London Rd., Reading, RG1 5AS, UK)  V.1-    1947-
   Volume(issue)/page/year: 100,283,1977
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 30 umol/L
REFERENCE :
   JGMIAN Journal of General Microbiology.  (Soc. for General Microbiology,
   Journal Sales, 62 London Rd., Reading, RG1 5AS, UK)  V.1-    1947-
   Volume(issue)/page/year: 100,283,1977
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 170 umol/L
REFERENCE :
   JGMIAN Journal of General Microbiology.  (Soc. for General Microbiology,
   Journal Sales, 62 London Rd., Reading, RG1 5AS, UK)  V.1-    1947-
   Volume(issue)/page/year: 100,271,1977
 
TYPE OF TEST            : Phage inhibition capacity
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 33 umol/L
REFERENCE :
   JGMIAN Journal of General Microbiology.  (Soc. for General Microbiology,
   Journal Sales, 62 London Rd., Reading, RG1 5AS, UK)  V.1-    1947-
   Volume(issue)/page/year: 100,271,1977
 
TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 5 ug/disc
REFERENCE :
   AEMIDF Applied and Environmental Microbiology.  (American Soc. for
   Microbiology, 1913 I St., NW, Washington, DC 20006)  V.31-    1976-
   Volume(issue)/page/year: 43,177,1982
 
                            *** END OF RECORD ***