*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NI6805000
CHEMICAL NAME           : Imidazole-5-methanol,
                          2-nitro-alpha,alpha,1-trimethyl-
CAS REGISTRY NUMBER     : 60628-92-4
BEILSTEIN REFERENCE NO. : 0882890
REFERENCE               : 5-23-11-00043 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C7-H11-N3-O3
MOLECULAR WEIGHT        : 185.21
WISWESSER LINE NOTATION : T5N CNJ A1 BNW EXQ1&1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-(2-Hydroxy-2-propyl)-1-methyl-2-nitroimidazole
   * Imidazole, 5-(2-hydroxy-2-propyl)-1-methyl-2-nitro-
   * L 12134
   * 2-Nitro-alpha,alpha,1-trimethylimidazole-5-methanol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 698 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Behavioral - ataxia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 21,781,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 475 mg/kg
TOXIC EFFECTS :
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - other oxidoreductases
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 20,1522,1977
 
                            *** END OF RECORD ***