*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NI4840000
CHEMICAL NAME           : Imidazole, 4-(2-(dimethylamino)ethyl)-
CAS REGISTRY NUMBER     : 673-46-1
LAST UPDATED            : 198305
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C7-H13-N3
MOLECULAR WEIGHT        : 139.23
WISWESSER LINE NOTATION : T5M CNJ D2N1&1
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 4-(2-Dimethylaminoethyl)imidazole
   * N,N-Dimethylhistamine
   * N',N'-Dimethylhistamine
   * N(sup alpha),N(sup alpha)-Dimethylhistamine
   * N(sup omega),N(sup omega)-Dimethylhistamine
   * SU-416
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 15 mg/kg
TOXIC EFFECTS :
   Cardiac - other changes
   Vascular - measurement of regional blood flow
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 87,33,1951
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 1 umol/L
REFERENCE :
   JIDEAE Journal of Investigative Dermatology.  (Williams & Wilkins Co., 428
   E. Preston St., Baltimore, MD 21202)  V.1-    1938- Volume(issue)/page/year:
   65,400,1975
 
                            *** END OF RECORD ***