*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NI4805800
CHEMICAL NAME           : 1H-Imidazole,
                          4,5-dihydro-2-(2-(1-naphthalenyl)ethyl)-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 103125-00-4
LAST UPDATED            : 198709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H16-N2.Cl-H
MOLECULAR WEIGHT        : 248.78
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Imidazoline, 2-(2-(1-naphthyl)ethyl)-, monohydrochloride
   * K-4300
   * 2-(2-(1-Naphthyl)ethyl)-2-imidazoline hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 88900 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JOPHDQ Journal of Pharmacobio-Dynamics.  (Japan Pub. Trading Co. (USA), 1255
   Howard St., San Francisco, CA 94103)  V.1-    1978- Volume(issue)/page/year:
   9,395,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 36700 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JOPHDQ Journal of Pharmacobio-Dynamics.  (Japan Pub. Trading Co. (USA), 1255
   Howard St., San Francisco, CA 94103)  V.1-    1978- Volume(issue)/page/year:
   9,395,1986
 
                            *** END OF RECORD ***