*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NI3092000
CHEMICAL NAME           : 1H-Imidazol-2-amine,
                          4,5-dihydro-N-1,3-benzodioxol-4-yl-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 103124-97-6
LAST UPDATED            : 198709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H11-N3-O2.Cl-H
MOLECULAR WEIGHT        : 241.70
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4,5-Dihydro-N-1,3-benzodioxol-4-yl-1H-imidazol-2-amine hydrochloride
   * 1H-Imidazole, 4,5-dihydro-2-((1,3-benzodioxol-4-yl)amino)-,  
   monohydrochloride
   * 2-Imidazoline, 2-(2,3-(methylenedioxy)anilino)-, monohydrochloride
   * K-6343
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - tremor
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JOPHDQ Journal of Pharmacobio-Dynamics.  (Japan Pub. Trading Co. (USA), 1255
   Howard St., San Francisco, CA 94103)  V.1-    1978- Volume(issue)/page/year:
   9,395,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 33 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JOPHDQ Journal of Pharmacobio-Dynamics.  (Japan Pub. Trading Co. (USA), 1255
   Howard St., San Francisco, CA 94103)  V.1-    1978- Volume(issue)/page/year:
   9,395,1986
 
                            *** END OF RECORD ***