*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NI0700000
CHEMICAL NAME           : Ilex cornuta lindl., leaf extract
LAST UPDATED            : 199504
DATA ITEMS CITED        : 3
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
                          Natural Product
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 1040 mg/kg
SEX/DURATION            : female 7-8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
REFERENCE :
   CYTPDT Zhongyao Tongbao.  Bulletin of Chinese Materia Medica.  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China)
   V.1-13, 1955-88 Suspended 1960-80(?). For Publisher information, see ZZZAE3
   Volume(issue)/page/year: 13,304,1988
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 1 gm/kg
SEX/DURATION            : female 16-17 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   CYTPDT Zhongyao Tongbao.  Bulletin of Chinese Materia Medica.  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China)
   V.1-13, 1955-88 Suspended 1960-80(?). For Publisher information, see ZZZAE3
   Volume(issue)/page/year: 13,304,1988
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 3600 mg/kg
SEX/DURATION            : female 11-13 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - abortion
   Reproductive - Effects on Embryo or Fetus - fetal death
   Reproductive - Effects on Embryo or Fetus - other effects to embryo
REFERENCE :
   CYTPDT Zhongyao Tongbao.  Bulletin of Chinese Materia Medica.  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China)
   V.1-13, 1955-88 Suspended 1960-80(?). For Publisher information, see ZZZAE3
   Volume(issue)/page/year: 13,304,1988
 
                            *** END OF RECORD ***