*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NH6737200
CHEMICAL NAME           : Ibogamine-18-carboxylic acid,
                          12-methoxy-13-((3-alpha)-17-methoxy-17-oxovobasan-3-y
                          l)-, methyl ester, 2-oxo-3-bornanesulfonate
LAST UPDATED            : 198609
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C43-H52-N4-O5.C10-H16-O4-S
MOLECULAR WEIGHT        : 937.31
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * CSV
   * Vocamine camphorsulfonate
   * Vocamine camphosulfonate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 46 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   APFRAD Annales Pharmaceutiques Francaises.  (SPPIF, B.P.22, F-41353 Vineuil,
   France)  V.1-    1943-  Volume(issue)/page/year: 15,617,1957
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 568 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - cyanosis
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 12,635,1957
 
                            *** END OF RECORD ***