*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : NC3450000
CHEMICAL NAME           : Hydroxylamine, N,O-diacetyl-N-(p-styrylphenyl)-, (E)-
CAS REGISTRY NUMBER     : 26488-34-6
BEILSTEIN REFERENCE NO. : 2751068
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C18-H17-N-O3
MOLECULAR WEIGHT        : 295.36
WISWESSER LINE NOTATION : 1VONV1&R D1U1R  -T
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * trans-N-Acetoxy-4-acetyl-aminostilbene
   * trans-N,O-Diacetyl-N-(p-styrylphenyl)hydroxylamine
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 180 mg/kg/20W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Sense Organs and Special Senses (Ear) - effect, not otherwise specified
REFERENCE :
   ZEKBAI Zeitschrift fuer Krebsforschung.  (Berlin, Fed. Rep. Ger.)  V.1-75,
   1903-71.  For publisher information, see JCROD7.  Volume(issue)/page/year:
   74,200,1970
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Gene conversion and mitotic recombination
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 10 ppm
REFERENCE :
   ZEKBAI Zeitschrift fuer Krebsforschung.  (Berlin, Fed. Rep. Ger.)  V.1-75,
   1903-71.  For publisher information, see JCROD7.  Volume(issue)/page/year:
   74,412,1970
 
TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 1 umol/L
REFERENCE :
   CBTOE2 Cell Biology and Toxicology.  (Princeton Scientific Pub., Inc., 301
   N. Harrison St., CN 5279, Princeton, NJ 08540)  V.1-    1984-
   Volume(issue)/page/year: 2,213,1986

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: S cerevisiae gene conversion; S
   cerevisiae-homozygosis
   
   EPA GENETOX PROGRAM 1988, Positive: S cerevisiae-reversion

 
                            *** END OF RECORD ***