*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MV1720450
CHEMICAL NAME           : Hydrazinecarboxylic acid,
                          1,2,3,4,6,11-hexahydro-(1-(4-((3-amino-2,3,6-trideoxy
                          -alpha-L-lyxo-
                          hexopyranosyl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-d
                          ioxo-2-naphthacenyl)e thylidene)-, 1,1-dimethylethyl
                          ester, (2S-cis)-, hydrochloride
LAST UPDATED            : 199603
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C32-H39-N3-O11.Cl-H
MOLECULAR WEIGHT        : 678.20
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 13-tert-Butoxycarbonylhydrazone rubomycin hydrochloride
   * Daunorubin 13-tert-butoxycarbonylhydrazone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 38 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   ANTBAL Antibiotiki.  (Moscow, USSR)  V.1-29, 1956-84.  For publisher
   information, see AMBIEH.  Volume(issue)/page/year: 26,813,1981
 
                            *** END OF RECORD ***