*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MR8157200
CHEMICAL NAME           : Hippuric acid, p-amino-, monosodium salt
CAS REGISTRY NUMBER     : 94-16-6
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H9-N2-O3.Na
MOLECULAR WEIGHT        : 216.19
WISWESSER LINE NOTATION : ZR DVM1VQ &-NA-
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * N-(4-Aminobenzoyl)glycine monosodium salt
   * p-Aminohippurate sodium
   * p-Aminohippuric acid sodium salt
   * Glycine, N-(4-aminobenzoyl)-, monosodium salt
   * Sodium p-aminohippurate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4075 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,828,1990
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4930 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - spastic paralysis with or without sensory
   change
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 84,147,1945
 
                            *** END OF RECORD ***