*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MU7400000
CHEMICAL NAME           : Hydrazine, 1-acetyl-2-isonicotinoyl-
CAS REGISTRY NUMBER     : 1078-38-2
BEILSTEIN REFERENCE NO. : 0154108
REFERENCE               : 4-22-00-00606 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C8-H9-N3-O2
MOLECULAR WEIGHT        : 179.20
WISWESSER LINE NOTATION : T6NJ BVMMV1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Acetyl isoniazid
   * N-Acetylisoniazid
   * 1-Acetyl-2-isonicotinoylhydrazine
   * N-Acetylisonicotinylhydrazide
   * 4-Pyridinecarboxylic acid, 2-acetylhydrazide
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 380 gm/kg/68W-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   EJCAAH European Journal of Cancer.  (Oxford, UK)  V.1-17(6), 1965-1981. For
   publisher information, see EJCODS.  Volume(issue)/page/year: 9,285,1973
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
REFERENCE :
   IJEBA6 Indian Journal of Experimental Biology.  (Publications & Information
   Directorate, CSIR, Hillside Rd., New Delhi 110 012, India)  V.1-    1963-
   Volume(issue)/page/year: 19,939,1981

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Inconclusive: Host-mediated assay

 
                            *** END OF RECORD ***