*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MS3450700
CHEMICAL NAME           : Histone III (calf thymus)
CAS REGISTRY NUMBER     : 9064-47-5
LAST UPDATED            : 198510
DATA ITEMS CITED        : 1
SYNONYMS/TRADE NAMES :
   * F3 histone fraction
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - effect, not otherwise
   specified
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 149,374,1964
 
                            *** END OF RECORD ***