*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MP2620000
CHEMICAL NAME           : 3-Hexanone, 6-(dimethylamino)-4,4-diphenyl-5-methyl-,
                          hydrochloride, (S)-
CAS REGISTRY NUMBER     : 7487-81-2
LAST UPDATED            : 199509
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H27-N-O.Cl-H
MOLECULAR WEIGHT        : 345.95
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6-(Dimethylamino)-4,4-diphenyl-5-methyl-3-hexanone hydrochloride (S)-
   * 3-Hexanone, 6-(dimethylamino)-5-methyl-4,4-diphenyl-, hydrochloride, (-)-
   * (-)-Isomethadone hydrochloride
   * l-Isomethadone hydrochloride
   * Levoisomethadone hydrochloride
   * NIH 2961
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 104 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 110,135,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 56800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JOCEAH Journal of Organic Chemistry.  (American Chemical Soc., Distribution
   Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037)  V.1-
   1936-  Volume(issue)/page/year: 17,1210,1952
 
                            *** END OF RECORD ***