*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MF8200000
CHEMICAL NAME           : 5'-Guanilic acid, disodium salt, mixed with disodium
                          5'-inosinate
CAS REGISTRY NUMBER     : 80702-47-2
LAST UPDATED            : 199601
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H12-N4-O8-P.2Na.C10-H11-N4-O8-P.2Na
MOLECULAR WEIGHT        : 1100.66
WISWESSER LINE NOTATION : T56 BN DN FN HMVJ D- BT5OTJ CQ DQ E1OPWO &T56 BN DN
                          FN HMVJ GZ D- BT5OTJ CQ DQ E1OPWO &-NA- 4
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Disodium 5'-guanylate mixed with disodium 5'-inosinate (1:1)
   * Disodium 5'-inosinate mixed with disodium 5'-guanylate (1:1)
   * Disodium 5'-ribonucleotide
   * 5'-Inosinic acid, disodium salt, mixed with disodium 5'-guanylate (1:1)
   * Ribotide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3800 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   TAKHAA Takeda Kenkyusho Ho.  Journal of the Takeda Research Laboratories.
   (Takeda Yakuhin Kogyo K.K., 2-17-85 Jusohon-machi, Yodogawa-ku, Osaka 532,
   Japan)  V.29-    1970-  Volume(issue)/page/year: 33,24,1974
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 8750 mg/kg
SEX/DURATION            : multigenerations
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - weaning or lactation index (e.g., #
   alive at weaning per # alive at day 4)
   Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
   gain)
REFERENCE :
   TXCYAC Toxicology.  (Elsevier Scientific Pub. Ireland, Ltd., POB 85,
   Limerick, Ireland) V.1-    1973-  Volume(issue)/page/year: 3,333,1975
 
                            *** END OF RECORD ***