*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MF6690000
CHEMICAL NAME           : Guanidine, 1-(p-trifluoromethylbenzyl)-,
                          hemihydrogensulfate
CAS REGISTRY NUMBER     : 14629-09-5
LAST UPDATED            : 199007
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C9-H10-F3-N3.1/2H2-O4-S
MOLECULAR WEIGHT        : 266.28
WISWESSER LINE NOTATION : MUYZM1R DXFFF 2 &..H2.S-O4
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * p-(Trifluoromethylbenzyl)guanidine
   * 1-(p-Trifluoromethylbenzyl)guanidine hemihydrogensulfate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 475 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,833,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - cyanosis
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,833,1967
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 10,833,1967
 
                            *** END OF RECORD ***