*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MF4230000
CHEMICAL NAME           : Guanidine, methyl- mixed with sodium nitrite
CAS REGISTRY NUMBER     : 65272-47-1
LAST UPDATED            : 199410
DATA ITEMS CITED        : 2
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Methylguanidine mixed with sodium nitrite (1:1)
   * Sodium nitrite mixed with methylguanidine (1:1)
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 70 gm/kg/63W-C
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
REFERENCE :
   ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie.  (Berlin,
   Fed. Rep. Ger.)  V.76-92, 1971-78.  For publisher information, see JCROD7.
   Volume(issue)/page/year: 90,87,1977
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 80 mmol/L
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   65,45,1974
 
                            *** END OF RECORD ***