*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MF3620650
CHEMICAL NAME           : Guanidine, (3-hydroxypropyl)-, p-nitrobenzoate
                          (ester), monohydrochloride
CAS REGISTRY NUMBER     : 19623-20-2
LAST UPDATED            : 198612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C11-H14-N4-O4.Cl-H
MOLECULAR WEIGHT        : 302.75
WISWESSER LINE NOTATION : WNR DVO3MYZUM &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * HM-200
   * (3-Hydroxypropyl)guanidine p-nitrobenzoate (ester) hydrochloride
   * 3-(p-Nitro-benzoyloxy)propylguanidine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 175,193,1968
 
                            *** END OF RECORD ***