*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ME1200000
CHEMICAL NAME           : Grayanotoxan-6-one,
                          10,20-didehydro-3,5,14,16-tetrahydroxy-,
                          (3-beta,14R)-
CAS REGISTRY NUMBER     : 28371-51-9
BEILSTEIN REFERENCE NO. : 2674036
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H30-O5
MOLECULAR WEIGHT        : 350.50
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * 6-Dehydrograyanotoxin II
   * (3-beta,14R)-10,20-Didehydro-3,5,14,16-tetrahydroxygrayanotoxan-6-one
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
   Behavioral - muscle contraction or spasticity
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   35,303,1976
 
                            *** END OF RECORD ***