*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ME1101000
CHEMICAL NAME           : Grayanotoxane-3,5,6,10,14,16-hexol, cyclic
                          5,6-(ethylidene acetal), (3-beta,6-beta,14R)-
CAS REGISTRY NUMBER     : 59236-85-0
LAST UPDATED            : 199406
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H36-O6
MOLECULAR WEIGHT        : 396.58
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * 5,6-Ethylidene-grayanotoxin III
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
   Behavioral - muscle contraction or spasticity
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   35,303,1976
 
                            *** END OF RECORD ***