*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AU0840000
CHEMICAL NAME           : Actinomycin 5898
LAST UPDATED            : 199609
DATA ITEMS CITED        : 2
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 915 ug/kg
TOXIC EFFECTS :
   Blood - changes in spleen
   Gastrointestinal - hypermotility, diarrhea
   Gastrointestinal - other changes
REFERENCE :
   ANTBAL Antibiotiki.  (Moscow, USSR)  V.1-29, 1956-84.  For publisher
   information, see AMBIEH.  Volume(issue)/page/year: 1(4),5,1956
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1250 ug/kg/5D-I
TOXIC EFFECTS :
   Related to Chronic Data - death
REFERENCE :
   ANTBAL Antibiotiki.  (Moscow, USSR)  V.1-29, 1956-84.  For publisher
   information, see AMBIEH.  Volume(issue)/page/year: 1(4),5,1956
 
                            *** END OF RECORD ***