*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR7145500
CHEMICAL NAME           : 9-Acridinamine, N,N-dimethyl-1-nitro-, hydrochloride
CAS REGISTRY NUMBER     : 28743-45-5
LAST UPDATED            : 199707
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C15-H13-N3-O2.Cl-H
MOLECULAR WEIGHT        : 303.77
WISWESSER LINE NOTATION : T C666 BNJ GNW IN1&1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * C 702
   * 1-Nitro-9-(dimethylamino)-acridine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 24 mg/kg
TOXIC EFFECTS :
   Behavioral - tetany
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   22,823,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1450 ug/kg
TOXIC EFFECTS :
   Behavioral - tetany
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   22,823,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17500 ug/kg
TOXIC EFFECTS :
   Behavioral - tetany
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   22,823,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3700 ug/kg
TOXIC EFFECTS :
   Behavioral - tetany
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   22,823,1974
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Bird - pigeon
DOSE/DURATION           : 3700 ug/kg
TOXIC EFFECTS :
   Gastrointestinal - nausea or vomiting
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   28,777,1980
 
                            *** END OF RECORD ***