*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR7145400
CHEMICAL NAME           : 9-Acridinamine, N,N-dimethyl-1-nitro-,
                          dihydrochloride
CAS REGISTRY NUMBER     : 63944-10-5
LAST UPDATED            : 198910
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C15-H13-N3-O2.2Cl-H
MOLECULAR WEIGHT        : 340.23
WISWESSER LINE NOTATION : T C666 BNJ GNW IN1&1 &GH 2
SYNONYMS/TRADE NAMES :
   * C-702
   * 1-Nitro-9-(dimethylamine)-acridine dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 23700 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   MMDPA6 Materia Medica Polona (English Edition).  (Ars Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.1-    1969-  Volume(issue)/page/year: 8,252,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1400 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   MMDPA6 Materia Medica Polona (English Edition).  (Ars Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.1-    1969-  Volume(issue)/page/year: 8,252,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 17500 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   MMDPA6 Materia Medica Polona (English Edition).  (Ars Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.1-    1969-  Volume(issue)/page/year: 8,252,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3700 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   MMDPA6 Materia Medica Polona (English Edition).  (Ars Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.1-    1969-  Volume(issue)/page/year: 8,252,1976
 
                            *** END OF RECORD ***