*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR9532000
CHEMICAL NAME           : Acridine, 1,2,3,4-tetrahydro-5-amino-
CAS REGISTRY NUMBER     : 3198-41-2
LAST UPDATED            : 199706
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C13-H14-N2
MOLECULAR WEIGHT        : 198.29
WISWESSER LINE NOTATION : T C666 BNT&&J NZ
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * 5-Amino-1,2,3,4-tetrahydroacridine
   * 4-Amino-2,3-tetramethylenequinoline
   * 1,2,3,4-Tetrahydro-5-aminoacridine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 30 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Gastrointestinal - changes in structure or function of salivary glands
   Skin and Appendages - hair
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 9,483,1966
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 781 ug/plate
REFERENCE :
   DDREDK Drug Development Research.  (Alan R. Liss, Inc., 41 E. 11th St., New
   York, NY 10003) V.1-    1981-  Volume(issue)/page/year: 14,91,1988
 
                            *** END OF RECORD ***