*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR9483600
CHEMICAL NAME           : Acridine,
                          1,2,3,4,4a,9,9a,10-octahydro-10-dimethylaminopropyl-,
                          (E)-, maleate
CAS REGISTRY NUMBER     : 18705-19-6
LAST UPDATED            : 199012
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H28-N2.C4-H4-O4
MOLECULAR WEIGHT        : 388.56
WISWESSER LINE NOTATION : T C666 BN&TTJ B3N1&1 &QV1U1VQ -C
SYNONYMS/TRADE NAMES :
   * trans-10-Dimethylaminopropyl-1,2,3,4,4a,9,9a,10-octahydroacridine maleate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 31,206,1968
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 52 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - effect, not otherwise specified
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   RPTOAN Russian Pharmacology and Toxicology (English Translation).
   Translation of FATOAO.  (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey,
   UK)  V.30-    1967-  Volume(issue)/page/year: 31,206,1968
 
                            *** END OF RECORD ***