*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR9246000
CHEMICAL NAME           : Acridine,
                          9-((3-(dimethylamino)propyl)amino)-1-nitro-,
                          10-oxide, dihydrochloride
CAS REGISTRY NUMBER     : 20064-38-4
LAST UPDATED            : 198910
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C18-H20-N4-O3.2Cl-H
MOLECULAR WEIGHT        : 413.34
WISWESSER LINE NOTATION : T C666 BNJ BO GNW IM3N1&1 &GH 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * C-666
   * Dihydrochloride N(sup 10)-oxide  
   1-nitro-9-(3-dimethylaminopropylamino)-acridine
   * 1-Nitro-9-(3-dimethylaminopropylamine)-acridine, N(sup 10)-oxide  
   dihydrochloride
   * 1,3-Propanediamine, N,N-dimethyl-N'-(1-nitro-9-acridinyl)-, N-oxide,  
   dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 110 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   MMDPA6 Materia Medica Polona (English Edition).  (Ars Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.1-    1969-  Volume(issue)/page/year: 8,252,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5400 ug/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   MMDPA6 Materia Medica Polona (English Edition).  (Ars Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.1-    1969-  Volume(issue)/page/year: 8,252,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 108 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   MMDPA6 Materia Medica Polona (English Edition).  (Ars Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.1-    1969-  Volume(issue)/page/year: 8,252,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   MMDPA6 Materia Medica Polona (English Edition).  (Ars Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.1-    1969-  Volume(issue)/page/year: 8,252,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Bird - pigeon
DOSE/DURATION           : 9000 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   28,777,1980
 
                            *** END OF RECORD ***