*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR9065000
CHEMICAL NAME           : Acridine, 3,6-diamino-, sulfate (1:1)
CAS REGISTRY NUMBER     : 553-30-0
LAST UPDATED            : 199603
DATA ITEMS CITED        : 8
MOLECULAR FORMULA       : C13-H11-N3.H2-O4-S
MOLECULAR WEIGHT        : 307.35
WISWESSER LINE NOTATION : T C666 BNJ EZ MZ &..H2.S-O4
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 3,6-Acridinediamine sulfate
   * 3,6-Acridinediamine, sulfate (1:1)
   * 3,6-Acridinediamine sulphate
   * 3,6-Diaminoacridine bisulphate
   * 3,6-Diaminoacridine sulphate (1:1)
   * 3,6-Diaminoacridinium monohydrogen sulphate
   * 2,8-Diaminoacridinium sulphate
   * Isoflav
   * Neutral proflavine sulphate
   * Pancridine
   * Proflavine (sulfate)
   * Proflavine sulphate
   * Proflavin sulfate
   * Sanoflavin
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 50 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 40,203,1976
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 500 ug/disc
REFERENCE :
   APMBAY Applied Microbiology.  (Washington, DC)  V.1-30, 1953-75.  For
   publisher information, see AEMIDF.  Volume(issue)/page/year: 6,23,1958
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 50 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 131,101,1984
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 5 mg/L
REFERENCE :
   MGGEAE Molecular and General Genetics.  (Springer-Verlag, Heidelberger Pl.
   3, D-1000 Berlin 33, Fed. Rep. Ger.)  V.99-    1967-
   Volume(issue)/page/year: 150,301,1977
 
TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 500 ug/L/2H
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 59,61,1979
 
TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Mammal - species unspecified Lymphocyte
DOSE/DURATION           : 1 umol/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   8,113,1974

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X1153
       No. of Facilities: 188 (estimated)
       No. of Industries: 1
       No. of Occupations: 5
       No. of Employees: 19221 (estimated)
       No. of Female Employees: 18648 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: S cerevisiae gene conversion

 
                            *** END OF RECORD ***