*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR7690000
CHEMICAL NAME           : Acridine,
                          6-chloro-9-((3-((2-chloroethyl)thio)propyl)amino)-2-m
                          ethoxy-, hydrochloride
CAS REGISTRY NUMBER     : 99711-15-6
LAST UPDATED            : 199109
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H20-Cl2-N2-O-S.xCl-H
MOLECULAR WEIGHT        : 650.59
WISWESSER LINE NOTATION : T C666 BNJ EG IM3S2G LO1 &GH
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 6-Chloro-9-(3-(2-chloroethyl)mercaptopropylamino)-2-methoxyacridine  
   hydrochloride
   * ICR 342
   * 2-Methoxy-6-chloro-9-(3-(2-chloroethyl)mercaptopropylamino)acridine  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 12 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   36,2423,1976
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6500 ug/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   36,2423,1976
 
                            *** END OF RECORD ***