*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR7525000
CHEMICAL NAME           : Acridine,
                          9-(2-(bis(2-chloroethyl)amino)ethylamino)-6-chloro-2-
                          methoxy-, dihydrochloride, hydrate
CAS REGISTRY NUMBER     : 10072-25-0
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H22-Cl3-N3-O.2Cl-H.H2-O
MOLECULAR WEIGHT        : 516.73
WISWESSER LINE NOTATION : T C666 BNJ EG IM2N2G2G LO1 &GH 2 &QH
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 9-(2-(Di(2-chloroethyl)amino)ethylamino)-6-chloro-2-methoxy-acridine
   * ICR-48b
   * NSC-34372
   * Quinacrine ethyl mustard
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 16 mg/kg/4W
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   36,915,1966
 
                            *** END OF RECORD ***