*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AR7515000
CHEMICAL NAME           : Acridine, 4,5-bis(aminomethyl)-, dihydrochloride
CAS REGISTRY NUMBER     : 55154-72-8
LAST UPDATED            : 199109
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H15-N3.2Cl-H
MOLECULAR WEIGHT        : 310.25
WISWESSER LINE NOTATION : T C666 BNJ D1Z N1Z &GH 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4,5-Acridinedimethanamine dihydrochloride
   * 4,5-Bis(aminomethyl)acridine dihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 18,320,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 54 mg/kg
TOXIC EFFECTS :
   Immunological Including Allergic - decrease in humoral immune response
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 18,320,1975
 
                            *** END OF RECORD ***