*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : MA3753000
CHEMICAL NAME           : Glutaric acid, 3-hydroxy-3-methyl-
CAS REGISTRY NUMBER     : 503-49-1
BEILSTEIN REFERENCE NO. : 1769194
REFERENCE               : 4-03-00-01166 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C6-H10-O5
MOLECULAR WEIGHT        : 162.16
WISWESSER LINE NOTATION : QV1XQ1&1VQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * CB-337
   * Dicrotalic acid
   * HMG
   * HMGA
   * beta-Hydroxy-beta-methylglutaric acid
   * 3-Hydroxy-3-methylglutaric acid
   * 3-Hydroxy-3-methylpentanedioic acid
   * Lipoglutaren
   * Medroglutaric acid
   * Meglutol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7330 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 25,1284,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3230 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 25,1284,1975
 
                            *** END OF RECORD ***