*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LZ5785000
CHEMICAL NAME           : Glucopyranoside,
                          3,5-dihydroxy-4-(3-hydroxy-4-methoxyhydrocinnamoyl)ph
                          enyl- 2-O-(6-deoxy-alpha-L-mannopyranosyl)-, beta-D-
CAS REGISTRY NUMBER     : 20702-77-6
LAST UPDATED            : 199312
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C28-H36-O15
MOLECULAR WEIGHT        : 612.64
WISWESSER LINE NOTATION : T6OTJ B1 CQ DQ EQ FO- CT6OTJ BOR CQ EQ DV2R CQ DO1&&
                          DQ EQ F1Q
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * NCI-C60764
   * Neohesperidin dihydrochalcone
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 365 mg/kg/13W-C
TOXIC EFFECTS :
   Gastrointestinal - other changes
   Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   FCTOD7 Food and Chemical Toxicology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.20-    1982- Volume(issue)/page/year:
   28,507,1990
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 89,69,1981

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Negative: Host-mediated assay

 
                            *** END OF RECORD ***