*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LZ6501000
CHEMICAL NAME           : Glucopyranosiduronic acid,
                          (5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-, methyl
                          ester, beta-D-
CAS REGISTRY NUMBER     : 64977-52-2
LAST UPDATED            : 199309
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C11-H13-F-N2-O8
MOLECULAR WEIGHT        : 320.26
SYNONYMS/TRADE NAMES :
   * (5-Fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-beta-D-glucopyranosiduronic  
   acid methyl ester
   * 5-Fluorouracil O-beta-D-glucuronide
   * FU-O-G
   * 5-FU O-beta-D-glucuronide
   * Methyl 1-(5-fluoro-1H-2-oxopyrimidin-4-yl)-beta-D-glucopyranuronate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   GANNA2 Gann.  Japanese Journal of Cancer Research.  (Tokyo, Japan)  V.1-75,
   1907-84.  For publisher information, see JJCREP.  Volume(issue)/page/year:
   69,283,1978
 
                            *** END OF RECORD ***