*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LZ4297000
CHEMICAL NAME           : Glucitol, 1-deoxy-1-(methylamino)-,
                          3,3'-(adipoyldiimino)bis(2,4,6-triiodobenzoate) (2:1)
                          (salt), D-
CAS REGISTRY NUMBER     : 3521-84-4
OTHER CAS REGISTRY NOS. : 36791-09-0
LAST UPDATED            : 199504
DATA ITEMS CITED        : 7
MOLECULAR FORMULA       : C20-H14-I6-N2-O6.2C7-H17-N-O5
MOLECULAR WEIGHT        : 1530.26
WISWESSER LINE NOTATION : QVR BI DI FI CMV4VMR BI DI FI CVQ &Q1YQYQYQYQ1M1 2
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Adipiodone meglumine
   * Biligrafin forte
   * Cavumbren
   * Cholograf-N-methylglucamine
   * Endocistobil
   * Endografin
   * Endographin
   * Intrablix
   * Iodipamide meglumine
   * Iodipamide meglumine salt
   * Iodipamide methylglucamine salt
   * Meglumine iodipamide
   * Methyl glucamine biligrafin
   * Methyl glucamine iodipamide
   * Ultrabil
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,5,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1921 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 28,1011,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 26,921,1984
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3195 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   INVRAV Investigative Radiology.  (Lippincott/Harper, Journal Fulfillment
   Dept., 2350 Virginia Ave., Hagerstown, MD 21740)  V.1-    1966-
   Volume(issue)/page/year: 15,S142,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 1200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 28,996,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Parenteral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1446 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 28,1011,1973

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X4732
       No. of Facilities: 234 (estimated)
       No. of Industries: 1
       No. of Occupations: 2
       No. of Employees: 5501 (estimated)
       No. of Female Employees: 3644 (estimated)

 
                            *** END OF RECORD ***