*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LY4220000
CHEMICAL NAME           : Germacra-1(10),11(13)-dien-12-oic acid,
                          4,5-alpha-epoxy-6-beta-hydroxy-, gamma-lactone
CAS REGISTRY NUMBER     : 20554-84-1
LAST UPDATED            : 198512
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H20-O3
MOLECULAR WEIGHT        : 248.35
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 4,5-alpha-Epoxy-6-beta-hydroxygermacra-1(10),11(13)-dien-12-oic acid  
   gamma-lactone
   * Parthenolide
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 202 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   30,3005,1981
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 202 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   30,3005,1981
 
                            *** END OF RECORD ***