*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LW4430000
CHEMICAL NAME           : Gadolinium,
                          (10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-
                          1,4,7-triacetato(3-)- N(sup 1),N(sup 4),N(sup
                          7),N(sup 10),O(sup 1),O(sup 4),O(sup 7),O(sup 10))-
CAS REGISTRY NUMBER     : 120066-54-8
LAST UPDATED            : 199503
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H29-Gd-N4-O7
MOLECULAR WEIGHT        : 558.75
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Gadolinium-HP-DO3A
   * Gadoteridol
   * GD-HP-DO 3A
   * Prohance
   * SQ 32692
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5587 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   17,187,1992
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6146 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   17,187,1992
 
                            *** END OF RECORD ***