*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : LW4430000 CHEMICAL NAME : Gadolinium, (10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane- 1,4,7-triacetato(3-)- N(sup 1),N(sup 4),N(sup 7),N(sup 10),O(sup 1),O(sup 4),O(sup 7),O(sup 10))- CAS REGISTRY NUMBER : 120066-54-8 LAST UPDATED : 199503 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C17-H29-Gd-N4-O7 MOLECULAR WEIGHT : 558.75 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Gadolinium-HP-DO3A * Gadoteridol * GD-HP-DO 3A * Prohance * SQ 32692 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >5587 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 17,187,1992 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 6146 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 17,187,1992 *** END OF RECORD ***