*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LU3520070
CHEMICAL NAME           : 2(3H)-Furanone,
                          4,5-dihydro-4-acetyl-5-(p-chlorophenyl)-, (E)-
CAS REGISTRY NUMBER     : 83144-11-0
LAST UPDATED            : 199404
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H11-Cl-O3
MOLECULAR WEIGHT        : 238.68
WISWESSER LINE NOTATION : T5OVTJ DV1 ER DG -T
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * trans-4-Acetyl-5-(p-chlorophenyl)-4,5-dihydro-2(3H)-furanone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 18,301,1983
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Cardiac - other changes
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 18,301,1983
 
                            *** END OF RECORD ***