*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LQ9000000
CHEMICAL NAME           : Formic acid, methylpentylidenehydrazide
CAS REGISTRY NUMBER     : 57590-20-2
BEILSTEIN REFERENCE NO. : 2349798
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C7-H14-N2-O
MOLECULAR WEIGHT        : 142.23
WISWESSER LINE NOTATION : VHN1&NU5
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
SYNONYMS/TRADE NAMES :
   * Pentanal, N-formyl-N-methylhydrazone
   * Pentanal methylformylhydrazone
   * Pentylidene gyromitrin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 594 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Liver - other changes
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   45,429,1978
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 350 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NATWAY Naturwissenschaften.  (Springer-Verlag, Heidelberger Platz 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.1-    1913-  Volume(issue)/page/year:
   62,395,1975
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2600 mg/kg/52W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Blood - lymphoma, including Hodgkin's disease
REFERENCE :
   MYCPAH Mycopathologia.  (Kluwer Academic Pub. Group, Distribution Centre,
   POB 322, 3300 AH Dordrecht, Netherlands)  V.1-    1938-
   Volume(issue)/page/year: 98,83,1987
 
TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2600 mg/kg/52W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Liver - tumors
REFERENCE :
   MYCPAH Mycopathologia.  (Kluwer Academic Pub. Group, Distribution Centre,
   POB 322, 3300 AH Dordrecht, Netherlands)  V.1-    1938-
   Volume(issue)/page/year: 98,83,1987
 
                            *** END OF RECORD ***