*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LL5160000
CHEMICAL NAME           : Fluoren-9-amine, N-(2-chloroethyl)-N-ethyl-,
                          hydrochloride
CAS REGISTRY NUMBER     : 13929-01-6
LAST UPDATED            : 199012
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H18-Cl-N.Cl-H
MOLECULAR WEIGHT        : 308.27
WISWESSER LINE NOTATION : L B656J HN2&2G &GH
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * N-(2-Chloroethyl)-N-ethylfluoren-9-amine hydrochloride
   * N-(2-Chloroethyl)-N-ethyl-9-fluorenamine hydrochloride
   * 2-Chloro-N-(9-fluorenyl)diethylamine hydrochloride
   * Diethylamine, 2-chloro-N-(9-fluorenyl)-, hydrochloride
   * 9H-Fluoren-9-amine, N-(2-chloroethyl)-N-ethyl-, hydrochloride
   * N-(9-Fluorenyl)-N-ethyl-beta-chloroethylamine hydrochloride
   * SKF-501 hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 97,25,1949
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 20 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   ENDOAO Endocrinology (Baltimore).  (Williams & Wilkins Co., 428 E. Preston
   St., Baltimore, MD 21203) V.1-    1917-  Volume(issue)/page/year:
   74,309,1964
 
                            *** END OF RECORD ***