*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LK8645900
CHEMICAL NAME           : Flavone,
                          4'-fluoro-7-methoxy-3-methyl-8-(1-pyrrolidinylmethyl)
                          -
CAS REGISTRY NUMBER     : 86073-57-6
BEILSTEIN REFERENCE NO. : 6002066
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H22-F-N-O3
MOLECULAR WEIGHT        : 367.45
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4H-1-Benzopyran-4-one,  
   2-(4-fluorophenyl)-7-methoxy-3-methyl-8-(1-pyrrolidinylmethyl)-
   * 4'-Fluoro-7-methoxy-3-methyl-8-(1-pyrrolidinylmethyl)flavone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 243 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   ARPMAS Archiv der Pharmazie (Weinheim, Germany)  (VCH Pub., Inc., 303 NW
   12th Ave., Deerfield Beach, FL 33441)  V.51-261, 1835-1923; V.305-    1972-
   Volume(issue)/page/year: 316,421,1983
 
                            *** END OF RECORD ***