*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LK3641325
CHEMICAL NAME           : Fibroblast growth factor, basic, recombinant human,
                          KCB-1
LAST UPDATED            : 199806
DATA ITEMS CITED        : 3
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Basic fibroblast growth factor, recombinant human, KCB-1
   * KCB-1
   * Recombinant human basic fibroblast growth factor, KCB-1
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >80 mg/kg
TOXIC EFFECTS :
   Blood - changes in spleen
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 30,1605,1996
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >20 mg/kg
TOXIC EFFECTS :
   Blood - changes in spleen
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 30,1605,1996
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >40 mg/kg
TOXIC EFFECTS :
   Blood - changes in spleen
   Skin and Appendages - dermatitis, other (after systemic exposure)
REFERENCE :
   KSRNAM Kiso to Rinsho.  Clinical Report.  (Yubunsha Co., Ltd., 1-5, Kanda
   Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan)  V.1-    1960-
   Volume(issue)/page/year: 30,1605,1996
 
                            *** END OF RECORD ***