*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : LE5945000
CHEMICAL NAME           : Euphorbia serrata latex
SUBSTANCE DEFINITION :
   Acetone soluble fraction of latex from Euphorbia serrata
REFERENCE :
   TUMOAB Tumori.  (Casa Editrice Ambrosiana, Via G. Frua 6, 20146 Milan,
   Italy)  V.1-    1911-  Volume(issue)/page/year: 64,99,1978
LAST UPDATED            : 199506
DATA ITEMS CITED        : 1
COMPOUND DESCRIPTOR     : Tumorigen
                          Natural Product
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6400 mg/kg/16W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   TUMOAB Tumori.  (Casa Editrice Ambrosiana, Via G. Frua 6, 20146 Milan,
   Italy)  V.1-    1911-  Volume(issue)/page/year: 64,99,1978
 
                            *** END OF RECORD ***