*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KR6712700
CHEMICAL NAME           : Ethylamine,
                          2-(p-(1,2-diphenyl-1-butenyl)phenoxy)-N-methyl-, (Z)-
CAS REGISTRY NUMBER     : 31750-48-8
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C25-H27-N-O
MOLECULAR WEIGHT        : 357.53
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Desmethyltamoxifen
   * N-Desmethyltamoxifen
   * cis-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine
   * Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N-methyl-, (Z)-
   * ICI 55,548
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 50 ug/kg
SEX/DURATION            : female 4 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - pre-implantation mortality (e.g. reduction in
   number of implants per female; total number of implants per corpora lutea)
REFERENCE :
   CTRRDO Cancer Treatment Reports.  (Washington, DC)  V.60-71, 1976-87.  For
   publisher information,  see JNCIEQ.  Volume(issue)/page/year: 64,741,1980
 
                            *** END OF RECORD ***