*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KQ8400000
CHEMICAL NAME           : Ethylamine,
                          2-((p-bromo-alpha-methyl-alpha-phenylbenzyl)oxy)-N,N-
                          dimethyl-, hydrochloride
CAS REGISTRY NUMBER     : 13977-28-1
LAST UPDATED            : 199103
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H22-Br-N-O.Cl-H
MOLECULAR WEIGHT        : 384.78
WISWESSER LINE NOTATION : ER DX1&R&O2N1&1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Bromadryl
   * 2-(1-(4-Bromodiphenyl)ethoxy)-N,N-dimethylethylamine hydrochloride
   * p-Bromo-alpha-methylbenzhydryl 2-dimethylaminoethyl ether hydrochloride
   * 2-((p-Bromo-alpha-methyl-alpha-phenylbenzyl)oxy)-N,N-dimethylethylamine  
   hydrochloride
   * 1-(p-Bromophenyl)-1-phenyl-1-(2-dimethylaminoethoxy)ethane hydrochloride
   * 2-(1-(4-Bromophenyl)-1-phenylethoxy)-N,N-dimethylethanamine hydrochloride
   * (2-(1-p-Bromophenyl-1-phenylethoxy)ethyl)dimethylethylamine hydrochloride
   * beta-Dimethylaminoethyl p-bromo-alpha-methylbenzhydryl ether  
   hydrochloride
   * Embramine hydrochloride
   * Mebrophenhydramine
   * Mebrophenhydramine hydrochloride
   * Mebryl
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 330 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals",
   11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year:
   11,556,1989
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals",
   11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year:
   11,556,1989
 
                            *** END OF RECORD ***