*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : KM5500500
CHEMICAL NAME           : 1,4-Ethanonaphtho(2,3-c:6,7-c')dipyran-9-acetic acid,
                          1,3,4,6,7,9,10,11-octahydro-3,7-
                          dimethyl-6,11-dioxo-4,5,12,13-tetrahydroxy-, methyl
                          ester, (1R-(1-alpha,3-beta,4-beta,7-
                          beta,9-alpha,13R*))-
CAS REGISTRY NUMBER     : 63972-31-6
LAST UPDATED            : 199512
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H24-O10
MOLECULAR WEIGHT        : 460.47
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Dihydrogranaticin methyl ester
   * Granatomycin A
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 28 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 11(1),435,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 28 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GEXXA8 German (East) Patent Document.  (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #147115
 
                            *** END OF RECORD ***